GENERAL CATALOGUE
Mazdutide
HY-P3375 · 1 mg
MedChemExpress · Cat: HY-P3375
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Catalog No: HY-P3375
CAS No: 2259884-03-0
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
Mazdutide IBI-362; LY-3305677 is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide GLP-1R and glucagon receptor GCGR . Mazdutide binds human and mouse GCGR Ki: 17.7 nM and 15.9 nM, respectively and GLP-1R Ki: 28.6 nM and 25.1 nM, respectively and stimulates insulin secretion from mouse islets EC50: 5.2 nM . Mazdutide is used in studies of obesity and type 2 diabetes T2D .
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