GENERAL CATALOGUE
MBL-IN-5
HY-173472 · 50 mg
MedChemExpress · Cat: HY-173472
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medchemexpress.com/mbl-in-5.htmlCatalog No: HY-173472
CAS No: 2876921-34-3
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
MBL-IN-5 is a metallo-?-lactamase MBL inhibitor. MBL-IN-5 inhibits three clinically relevant B1 subfamily MBLs NDM-1, VIM-1, and IMP-1 with IC50s of 0.05 ?nM, 14 ?nM and 21 nM respectively. MBL-IN-5 remarkably enhances carbapenemsAAasAasAa effectiveness against MBL-producing clinical strains and significantly reduces the bacterial load in a neutropenic murine thigh infection model combined with the IPM antibiotic.
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