GENERAL CATALOGUE
MBM-55
HY-101029 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-101029
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Catalog No: HY-101029
CAS No: 2083622-09-5
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
MBM-55 is a potent NIMA-related kinase 2 Nek2 inhibitor with an IC50 of 1 nM. MBM-55 shows a 20-fold or greater selectivity in most kinases with the exception of RSK1 IC50=5.4 nM and DYRK1a IC50=6.5 nM . MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-55 shows antitumor activities, and no obvious toxicity to mice.
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