GENERAL CATALOGUE
MBM-55S
HY-101029A · 50 mg
MedChemExpress · Cat: HY-101029A
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medchemexpress.com/mbm-55s.html
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Catalog No: HY-101029A
CAS No: 2083624-07-9
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
MBM-55S is a potent NIMA-related kinase 2 Nek2 inhibitor with an IC50 of 1 nM. MBM-55S shows a 20-fold or greater selectivity in most kinases with the exception of RSK1 IC50=5.4 nM and DYRK1a IC50=6.5 nM . MBM-55S effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-55S shows antitumor activities, and no obvious toxicity to mice.
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