GENERAL CATALOGUE
Mcl-1 inhibitor 20
HY-159588 · 50 mg
MedChemExpress · Cat: HY-159588
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Manufacturer product page
medchemexpress.com/mcl-1-inhibitor-20.htmlCatalog No: HY-159588
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Mcl-1 inhibitor 20 compound 47 is a Mcl-1 inhibitor with anti-leukemic effects. Mcl-1 inhibitor 20 can bind to the BH3 binding groove of Mcl-1 Ki=24 nM , occupy the P1 pocket in Mcl-1, and form interactions with Lys234 and Val249. Mcl-1 inhibitor 20 has good microsomal stability, pharmacokinetic characteristics and low cardiotoxicity.
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