GENERAL CATALOGUE
MCUF-651
HY-149453 · 5 mg
MedChemExpress · Cat: HY-149453
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Catalog No: HY-149453
CAS No: 2747162-85-0
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
MCUF-651 is an orally active guanylyl cyclase A receptor GC-A positive allosteric modulator PAM KD: 397 nM . MCUF-651 binds to GC-A and selectively enhances the binding of atrial natriuretic peptide ANP to GC-A. MCUF-651 enhances ANP-mediated cGMP generation in human cardiac, renal, and fat cells. MCUF-651 inhibits cardiomyocyte hypertrophy.
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