

HY-149250 · 50 mg
MedChemExpress · Cat: HY-149250
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Manufacturer product page
medchemexpress.com/mdmx-mdm2-in-2.html
Description
MDMX/MDM2-IN-2 is a potent p53-MDM2/MDMX dual inhibitors with Kis of 0.23 ?M and 2.45 ?M for MDM2 and MDMX, respectively. MDMX/MDM2-IN-2 inhibits the binding of p53 and MDM2 proteins. MDMX/MDM2-IN-2 restores the function of p53 and enables cell cycle arrest and apoptosis. MDMX/MDM2-IN-2 inhibits cell migration and invasion. MDMX/MDM2-IN-2 has antitumor activity.







