GENERAL CATALOGUE
ME-344
HY-112749 · 5 mg
MedChemExpress · Cat: HY-112749
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medchemexpress.com/me-344.htmlCatalog No: HY-112749
CAS No: 1374524-68-1
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
ME-344 is a mitochondrial Heme oxygenase 1 HO-1 inhibitor. ME-344 specifically binds and alters HO-1 structure, and increases HO-1 translocation from the rough endoplasmic reticulum to mitochondria, but only in drug-sensitive cells such as H460 and SHP-77 cells . ME-344 decreases mitochondrial ATP production and induces ROS, with subsequent disruption of redox homeostasis and mitochondrial function. ME-344 has significant antitumor activity, and can be used for cancers like breast cancer research.
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