

APRab00432-20μL · 20μL
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Description
EnkiLife offers the Melatonin Receptor 1A Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for ICC/IF,ELISA application. Alternative Names of Immunogen: MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: ICC/IF 1:50-1:200,ELISA 1:5000-1:20000 Background: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. Research Area: Neuroscience







