GENERAL CATALOGUE
MELK-8a
HY-100368 · 5 mg
MedChemExpress · Cat: HY-100368
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Catalog No: HY-100368
CAS No: 1922153-17-0
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
MELK-8a NVS-MELK8a is a highly potent and selective maternal embryonic leucine zipper kinase MELK inhibitor with IC50 of 2 nM. MELK-8a also inhibits Flt3 ITD , Haspin, PDGFR? with IC50s of 0.18, 0.19, and 0.42 ?M, respectively. MELK plays an essential role in regulating cell mitosis in a subset of cancer cells.
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