MELK Rabbit Polyclonal Antibody

Description

EnkiLife offers the MELK Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat,Mouse species and is suitable for WB,IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: MELK; KIAA0175; Maternal embryonic leucine zipper kinase; hMELK; Protein kinase Eg3; pEg3 kinase; Protein kinase PK38; hPK38; Tyrosine-protein kinase MELK. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000 Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein. function:Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis. PTM:Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8. similarity:Belongs to the protein kinase superfamily. similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. similarity:Contains 1 KA1 (kinase-associated) domain. similarity:Contains 1 protein kinase domain. subunit:Interacts with ZNF622 and PPP1R8. tissue specificity:Expressed in placenta, kidney, thymus, testis, ovary and intestine.