GENERAL CATALOGUE
Meninμ"μ"KMT2A-IN-1
HY-170832 · 50 mg
MedChemExpress · Cat: HY-170832
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Manufacturer product page
medchemexpress.com/menin-kmt2a-in-1.htmlCatalog No: HY-170832
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
MeninAAasAasAaKMT2A-IN-1 Compound 20 is the inhibitor for meninAAasAasAaKMT2A that binds to menin with an IC50 of 8 nM, and inhibits the interaction between menin and lysine methyltransferase 2A KMT2A . MeninAAasAasAaKMT2A-IN-1 inhibits hERG with an IC50 of 65 ?M. MeninAAasAasAaKMT2A-IN-1 inhibits cell MV4-11 with an IC50 of 74 nM. MeninAAasAasAaKMT2A-IN-1 exhibits good pharmacokinetic characteristics in CD-1 mouse with an orally bioavailability of 74 %.
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