Menin-MLL inhibitor MI-2

Name: Menin-MLL inhibitor MI-2
Brand: MedChemExpress

HY-15222 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-15222

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medchemexpress.com/MI-2.html

Catalog No: HY-15222

CAS No: 1271738-62-5

Category: Apoptosis

Pack Size: Free Sample (0.1 - 0.2 mg)

Brand: MedChemExpress

Description

Menin-MLL inhibitor MI-2 is a competitive and selective Menin-MLL interaction inhibitor with an IC50 value of 446 nM and a Ki value of 158 nM. Menin-MLL inhibitor MI-2 downregulates the expression of target genes such as HOXA9 and MEIS1, inhibits proliferation of leukemia cells and induces apoptosis and differentiation. Menin-MLL inhibitor MI-2 is proming for rasearch of MLL-rearranged acute leukemias e.g., AML, ALL .