Menin Rabbit Monoclonal Antibody

Description

EnkiLife offers the Menin Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat species and is suitable for WB,IP application. Alternative Names of Immunogen: MEN1; SCG2; Menin. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IP 1:20-1:50 Background: Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL)-containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes. Research Area: Epigenetics and Nuclear Signaling