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Metarrestin
GENERAL CATALOGUE

Metarrestin

HY-120118 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-120118

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medchemexpress.com/metarrestin.html
Catalog No: HY-120118
CAS No: 1443414-10-5
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

Metarrestin ML246 is an orally active, first-in-class and specific perinucleolar compartment inhibitor. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase Pol I transcription, at least in part by interacting with the translation elongation factor eEF1A2. Metarrestin blocks metastatic development and extends survival in mouse cancer models.

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