

HY-120118 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-120118
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medchemexpress.com/metarrestin.htmlDescription
Metarrestin ML246 is an orally active, first-in-class and specific perinucleolar compartment inhibitor. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase Pol I transcription, at least in part by interacting with the translation elongation factor eEF1A2. Metarrestin blocks metastatic development and extends survival in mouse cancer models.





