Methacholine bromide

Description

Methacholine Acetyl-?-methylcholine bromide is a potent muscarinic-3 M3 agonist. Methacholine bromide acts directly on acetylcholine receptors on smooth muscle causing bronchoconstriction and airway narrowing. Methacholine bromide shows a high sensitivity to identify bronchial hyperresponsiveness BHR . Methacholine bromide can be used to measure airway hyperresponsiveness AHR as a diagnostic aid in the assessment of individuals with asthma-like symptoms and normal resting expiratory flow rates.