Methacholine iodide

Description

Methacholine iodide is a potent muscarinic-3 M3 agonist. Methacholine iodide acts directly on acetylcholine receptors on smooth muscle causing bronchoconstriction and airway narrowing. Methacholine iodide shows a high sensitivity to identify bronchial hyperresponsiveness BHR . Methacholine iodide can be used to measure airway hyperresponsiveness AHR as a diagnostic aid in the assessment of individuals with asthma-like symptoms and normal resting expiratory flow rates.