GENERAL CATALOGUE
Methoxyamine hydrochloride
HY-Y0958 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-Y0958
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Manufacturer product page
medchemexpress.com/methoxyamine-hydrochloride.htmlCatalog No: HY-Y0958
CAS No: 593-56-6
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Methoxyamine O-Methylhydroxylamine hydrochloride is an orally active and potent base excision repair BER inhibitor. Methoxyamine hydrochloride binds to 3AAasAasAa hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase MPG following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic AP sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents.
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