Methoxyamine hydrochloride (Standard)

Description

Methoxyamine hydrochloride Standard is the analytical standard of Methoxyamine hydrochloride . This product is intended for research and analytical applications. Methoxyamine O-Methylhydroxylamine hydrochloride is an orally active and potent base excision repair BER inhibitor. Methoxyamine hydrochloride binds to 3AAasAasAa hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase MPG following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic AP sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents.