GENERAL CATALOGUE
Methylnissolin
HY-N2484 · 1 mg
MedChemExpress · Cat: HY-N2484
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Catalog No: HY-N2484
CAS No: 73340-41-7
Category: MAPK ERK Pathway
Pack Size: 1 mg
Brand: MedChemExpress
Description
Methylnissolin Astrapterocarpan , isolated from Astragalus membranaceus, inhibits platelet-derived growth factor PDGF -BB-induced cell proliferation with an IC50 of 10 ?M. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 ERIC1/2 mitogen-activated protein MAP kinase. Methylnissolin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibition of the ERK1/2 MAP kinase cascade.
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