MG-132

Description

MG-132 GMP Z-Leu-Leu-Leu-al GMP is MG-132 HY-13259 produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-132 Z-Leu-Leu-Leu-al is a potent proteasome and calpain inhibitor with IC50s of 100 nM and 1.2 ?M, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis.