GENERAL CATALOGUE
mG2N001
HY-157998 · 50 mg
MedChemExpress · Cat: HY-157998
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medchemexpress.com/mg2n001.htmlCatalog No: HY-157998
CAS No: 2760515-88-4
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
mG2N001 is a negative allosteric modulator NAM IC50: 93 nM of the metabotropic glutamate receptor mGluR2 and binds to mGluR2 as an antagonist Ki: 63 nM . mG2N001 is microparticle- and plasma-stable, and its radioisotope 11C mG2N001 can be used in PET imaging. 11C mG2N001 has good brain heterogeneity and brain penetration, and can selectively accumulate in mGluR2-rich regions, producing high-contrast brain images.
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