GENERAL CATALOGUE
MGS0039
HY-123411 · 50 mg
MedChemExpress · Cat: HY-123411
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Catalog No: HY-123411
CAS No: 569686-87-9
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
MGS0039 is a type II group mGluR antagonist. MGS0039 has a high affinity for mGluR2 and mGluR3, with Ki values of 2.2 nM and 4.5 nM, respectively. MGS0039 can attenuate the inhibitory effect of glutamate-induced cyclic AMP formation triggered by Forskolin HY-15371 in CHO cells expressing mGluR2/mGluR3. MGS0039 shows antidepressant-like activity in rats.
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