GENERAL CATALOGUE
MHES0488A
HY-P991236 · 1 mg
MedChemExpress · Cat: HY-P991236
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Manufacturer product page
medchemexpress.com/mhes0488a.htmlCatalog No: HY-P991236
Category: Cell Cycle DNA Damage
Pack Size: 1 mg
Brand: MedChemExpress
Description
MHES0488A is a selective humanized antibody that targets HER2 with a KD value of 0.8 nM. MHES0488A is an antibody part of DHES0815A. MHES0488A is internalized by cells and transported to lysosomes, and then releases PBD-monoamide that enters the nucleus, alkylates DNA and induces DNA damage and apoptosis. MHES0488A is promising for research of cancers, such as HER2-positive breast cancer and gastric cancer.
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