GENERAL CATALOGUE
MI891
HY-175264 · 50 mg
MedChemExpress · Cat: HY-175264
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medchemexpress.com/mi891.html
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Catalog No: HY-175264
CAS No: 2530027-77-9
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
MI891 is a highly selective PXR antagonist IC50 = 3.76 ?M, Kd = 1.7 ?M and inverse agonist IC50 = 6.1 ?M . MI891 selectively disrupts the interaction between PXR and its coactivator SRC1. MI891 effectively inhibits Rifampicin HY-B0272 -induced PXR activation. MI891 is useful for the study of metabolic diseases and other diseases.
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