GENERAL CATALOGUE
Midostaurin
HY-10230 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-10230
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medchemexpress.com/PKC412.html
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Catalog No: HY-10230
CAS No: 120685-11-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Midostaurin PKC412; CGP 41251 is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCAZA+/-/AZA2/AZA3, Syk, , , , c-Kit, c-Fgr, c-Src, FLT3, PDFRAZA2 and VEGFR1/2 with IC50s ranging from 22-500 nM. Midostaurin also upregulates endothelial nitric oxide synthase gene expression. Midostaurin shows powerful anticancer effects.
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