

J64947MB ·
Thermo Fisher Scientific · Cat: J64947MB
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Description
MIF Antagonist, ISO-1 inhibits MIF dopachrome tautomerase activity by binding to its catalytic active site IC50 = 7 muM for D-dopachrome tautomerase and suppresses the production of TNFalpha, PGE2 and COX-2 in human monocytes and arachidonic acid in RAW 264.7 macrophages.







