GENERAL CATALOGUE
Migalastat
HY-14929 · 50 mg
MedChemExpress · Cat: HY-14929
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Catalog No: HY-14929
CAS No: 108147-54-2
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
Migalastat GR181413A free base is an orally active ?-galactosidase A molecular chaperone, with an IC50 value of 0.04 ?M for human ?-Gal A. Migalastat binds to the active site of certain unstable mutant forms of ?-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant ?-galactosidase A to exhibit biological activity.
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