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Migalastat hydrochloride-15N
GENERAL CATALOGUE

Migalastat hydrochloride-15N

HY-W740650 · 1 mg

MedChemExpress · Cat: HY-W740650

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Catalog No: HY-W740650
CAS No: 1219134-37-8
Category: Metabolic Enzyme Protease
Pack Size: 1 mg
Brand: MedChemExpress

Description

Migalastat hydrochloride-15N GR181413A-15N is the 15N-labeled Migalastat hydrochloride HY-14929A . Migalastat GR181413A free base hydrochloride is an orally active ?-galactosidase A molecular chaperone, with an IC50 value of 0.04 ?M for human ?-Gal A. Migalastat binds to the active site of certain unstable mutant forms of ?-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant ?-galactosidase A to exhibit biological activity.

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