Milnacipran-d5 hydrochloride

Description

Milnacipran-d5 hydrochloride is deuterium labeled Milnacipran hydrochloride HY-B0168A . Milnacipran hydrochloride is an orally active Serotonin HY-B1473A and Norepinephrine HY-13715 reuptake inhibitor. Milnacipran hydrochloride inhibits monoamine transporters, especially the norepinephrine transporter and the serotonin transporter Ki values of 31 and 8.5 nM, respectively . Milnacipran hydrochloride inhibits pERK1/2 activation. Milnacipran hydrochloride has antidepressant, anxiolytic and analgesic properties. Milnacipran hydrochloride inhibits biting behavior in mice. Milnacipran hydrochloride can be used in the study of major depressive disorder, anxiety disorders, and neuropathic pain e.g., fibromyalgia .