GENERAL CATALOGUE
Mirdametinib
HY-10254 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-10254
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medchemexpress.com/PD0325901.html
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Catalog No: HY-10254
CAS No: 391210-10-9
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Mirdametinib PD0325901 is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts.
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