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MiTMABTM, dynamin I and dynamin II inhibitor
ab120466 · 5 mg
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Catalog No: ab120466
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 336.4 Da. Cell-permeable dynamin I and dynamin II inhibitor IC50 values are 3.1 and 8.4 muM for inhibition of dynamin I and dynamin II GTPase, respectively . Targets the pleckstrin homology PH lipid binding domain. Competitive with phospholipid and non-competitive with GTP. Inhibits receptor-mediated and synaptic vesicle endocytosis IC50 values are 19.9 and 2.2 muM, respectively . Inhibits cancer cell growth.
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