GENERAL CATALOGUE
Mitoguazone
HY-106634 · 10 mM * 1 mL in Water
MedChemExpress · Cat: HY-106634
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medchemexpress.com/mitoguazone.htmlCatalog No: HY-106634
CAS No: 459-86-9
Category: Anti-infection
Pack Size: 10 mM * 1 mL in Water
Brand: MedChemExpress
Description
Mitoguazone Methylglyoxal-bis guanylhydrazone is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase SAMDC inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkins and non-Hodgkins lymphoma treatment.
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