Mitotane (Standard)

Description

Mitotane Standard is the analytical standard of Mitotane. This product is intended for research and analytical applications. Mitotane 2,4?-DDD , an isomer of DDD and derivative of dichlorodiphenyltrichloroethane DDT , is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol FC accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor SXR activation, and has agent-agent interactions.