

HY-161618 · 5 mg
MedChemExpress · Cat: HY-161618
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Manufacturer product page
medchemexpress.com/mj04.html
Description
MJ04 is a selective inhibitor for Janus Kinase 3 JAK 3 with an IC50 of 2.03 nM. MJ04 inhibits T cell differentation and inhibits the proinfammatory cytokines in Lipopolysaccharides HY-D1056 ?induced macrophages. MJ04 exhibits good pharmacokinetic characters in mice, promotes hair growth in DHT-induced androgenetic alopecia AGA in athymic mice model, without significant toxicity LD50 2 g/kg.



