GENERAL CATALOGUE
MK-0159
HY-150508 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-150508
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Catalog No: HY-150508
CAS No: 2641484-61-7
Category: Immunology Inflammation
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
MK-0159 is an orally active, potent and selective CD38 inhibitor, with IC50 values of 22, 3, and 70 nM for human, mouse and rat CD38, respectively. MK-0159 also shows good microsomal stability for human and rodent liver microsomes. MK-0159 increases NAD+ nicotinamide adenine dinucleotide and reduces ADPR adenosine diphosphate ribose in whole blood and heart.
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