GENERAL CATALOGUE
MK-0731
HY-50672 · 1 mg
MedChemExpress · Cat: HY-50672
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medchemexpress.com/mk-0731.html
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Catalog No: HY-50672
CAS No: 845256-65-7
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
MK-0731 is a selective, non-competitive and allosteric kinesin spindle protein KSP inhibitor with an IC50 of 2.2 nM and a pKa of 7.6. MK-0731 is >20,000 fold selectivity against other kinesins. MK-0731 induces mitotic arrest and induces apoptosis in tumors. MK-0731 provides significant antitumor efficacy.
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