

HY-108047 · 1 mg
MedChemExpress · Cat: HY-108047
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medchemexpress.com/mk-0873.htmlDescription
MK-0873 is a selective phosphodiesterase-4 PDE4 inhibitor. MK-0873 increases intracellular levels of cyclic adenosine phosphate cAMP by inhibiting the activity of the PDE4 enzyme and subsequently activates protein kinase A PKA . Activated PKA inhibits the activity of inflammatory cells and leads to direct relaxation of airway smooth muscle. MK-0873 can be used in studies of chronic obstructive pulmonary disease COPD .







