GENERAL CATALOGUE
ML216
HY-12342 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-12342
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Catalog No: HY-12342
CAS No: 1430213-30-1
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
ML216 CID-49852229 is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC50s of 2.98 ?M and 0.97 ?M for BLMfull-length and BLM636-1298, respectively. ML216 inhibits ssDNA-dependent ATPase activity of BLM with a Ki of 1.76 ?M. Antitumor avtivity.
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