GENERAL CATALOGUE
ML289
HY-19630 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-19630
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Catalog No: HY-19630
CAS No: 1382481-79-9
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
ML289 VU0463597 is a potent, selective, and CNS-penetrant mGlu3 IC50=0.66 ?M negative allosteric modulator. ML289 displays >15-fold selectivity over mGlu2 and is inactive against mGlu5. ML289 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition CuAAc with molecules containing Azide groups.
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