GENERAL CATALOGUE
ML291
HY-101991 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-101991
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Catalog No: HY-101991
CAS No: 1523437-16-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
ML291 is a UPR unfolded protein response -inducing sulfonamidebenzamide. ML291 overwhelms the adaptive capacity of the UPR and induces apoptosis in a variety of solid cancer models. ML291 can activate the PERK/eIF2a/CHOP apoptotic arm of the UPR and reduce leukemic cell burden.
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