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ML346
GENERAL CATALOGUE

ML346

HY-18669 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-18669

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medchemexpress.com/ML346.html
Catalog No: HY-18669
CAS No: 100872-83-1
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

ML346 is an activator of Hsp70 expression and HSF-1 activity, with an EC50 of 4.6 AZA14M for Hsp70. ML346 restores protein folding in conformational disease models, without significant cytotoxicity or lack of specificity. ML346 induces specific increases in genes and protein effectors of the heat shock response HSR , including chaperones such as Hsp70, Hsp40, and Hsp27.

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