GENERAL CATALOGUE
ML364
HY-100900 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-100900
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Catalog No: HY-100900
CAS No: 1991986-30-1
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
ML364 is a selective ubiquitin specific peptidase 2 USP2 inhibitor IC50=1.1 ?M with anti-proliferative activity, which direct binds to USP2 Kd=5.2 ?M , induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP.
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