GENERAL CATALOGUE
ML372
HY-124713 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-124713
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medchemexpress.com/ml372.html
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Catalog No: HY-124713
CAS No: 1331745-61-9
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
ML372 inhibits survival motor neuron SMN protein ubiquitination, increases SMN protein stability without affecting mRNA expression. ML372 improves spinal muscular atrophy SMA in mice. ML372 is brain penetrant and has a reasonable exposure and half-life in vivo.