MLH1 Rabbit Monoclonal Antibody

Description

EnkiLife offers the MLH1 Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,ICC/IF application. Alternative Names of Immunogen: MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,ICC/IF 1:50-1:200 Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. Research Area: Epigenetics and Nuclear Signaling