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MLi-2, LRRK2 inhibitor
ab254528 · 1 mg
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Catalog No: ab254528
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam
Description
MW 379.5 Da, Purity >98 %. Potent and selective LRRK2 inhibitor. Inhibits LRRK2 in cell-free IC50 = 0.76 nM , cell-based IC50 = 1.4 nM and radioligand-binding IC50 = 3.4 nM assays. Greater than 295-fold selective against a panel of receptors, channels and over 300 kinases. Oral dosing results in reduced Ser935 phosphorylation of LRRK2 in animal models.
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