GENERAL CATALOGUE
MLS1547
HY-128121 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-128121
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Catalog No: HY-128121
CAS No: 315698-36-3
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
MLS1547 is a highly efficacious G protein-biased dopamine D2 receptor D2R agonist Ki=1.2 ?M . MLS1547 stimulates D2R G protein-mediated signaling EC50=0.37 ?M in a calcium mobilization assay . MLS1547 acts as an antagonist for dopamine DA -stimulated ?-arrestin recruitment to the D2R IC50=9.9 ?M .
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