

HY-12220 · 2 mg
MedChemExpress · Cat: HY-12220
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medchemexpress.com/MM-102.htmlDescription
MM-102 HMTase Inhibitor IX is a cell-permeable and tightly binding inhibitor of MLL1-WDR5 interaction IC50=2.4 nM . MM-102 can specifically inhibit the growth and induce apoptosis of leukemia cells containing MLL1 fusion protein, and reduce renal fibrosis and inflammation in mice with ischemia-reperfusion injury. In addition, MM-102 also acts as an H3K4 histone methyltransferase inhibitor to improve the development of porcine somatic cell nuclear transfer SCNT embryos.







