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MNS
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MNS

HY-78263 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-78263

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medchemexpress.com/MNS.html
Catalog No: HY-78263
CAS No: 1485-00-3
Category: Cytoskeleton
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

MNS NSC 170724 , the beta-nitrostyrene derivative, is an orally active tyrosine kinase inhibitor and a broad-spectrum antiplatelet agent. MNS inhibits Src, Syk, and FAK with IC50 of 27.3, 2.8, and 97.6 ?M, respectively. MNS inhibits NLRP3 inflammasome and ?1 integrin. MNS completely inhibits U46619, ADP-, arachidonic acid-, collagen-, and thrombin-induced platelet aggregation with IC50 values of 2.1, 4.1, 5.8, 7.0, and 12.7 ?M, respectively. MNS is cytotoxic to a variety of cells.

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