GENERAL CATALOGUE
Modakafusp alfa
HY-P99744 · 1 mg
MedChemExpress · Cat: HY-P99744
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Catalog No: HY-P99744
CAS No: 2254522-19-3
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
Modakafusp alfa TAK-573 is a humanized, anti-CD38 IgG4 monoclonal antibody fused to 2 attenuated IFN?2b molecules, which delivers interferon-alpha to CD38-expressing cells. Modakafusp alfa has direct anti-proliferative activity on multiple myeloma MM cancer cells in vitro and induces robust and durable antitumor responses in MM xenograft tumor models. Modakafusp alfa in combination with anti-PD-1 antibodies induces immunomodulation and antitumor responses with good tolerance in mice.
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